Proteolipid Protein 1 (PLP1) (N-Term) Peptide
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- Target See all PLP1 products
- PLP1 (Proteolipid Protein 1 (PLP1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PLP1 antibody (Catalog #: ARP33843_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PLP1 (Proteolipid Protein 1 (PLP1))
- Synonyms
- GPM6C Peptide, HLD1 Peptide, MMPL Peptide, PLP Peptide, PLP/DM20 Peptide, PMD Peptide, SPG2 Peptide, Plp Peptide, PLP1 Peptide, plp1 Peptide, DKFZp459O081 Peptide, DKFZp459O113 Peptide, DM20 Peptide, jimpy Peptide, jp Peptide, msd Peptide, rsh Peptide, plp Peptide, hld1 Peptide, mmpl Peptide, plp1a Peptide, pmd Peptide, spg2 Peptide, DMalpha2c Peptide, wu:fc27f01 Peptide, wu:fj36d03 Peptide, wu:fj42d08 Peptide, zgc:110499 Peptide, PLP-B Peptide, plp1-a Peptide, plp1-b Peptide, plp1b Peptide, proteolipid protein 1 Peptide, proteolipid protein (myelin) 1 Peptide, myelin proteolipid protein Peptide, proteolipid protein 1 L homeolog Peptide, proteolipid protein 1a Peptide, proteolipid protein 1 S homeolog Peptide, PLP1 Peptide, Plp1 Peptide, plp1 Peptide, Tsp_11640 Peptide, plp Peptide, plp1.L Peptide, plp1a Peptide, plp1.S Peptide
- Background
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PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.
Alias Symbols: MMPL, PLP, PLP/DM20, PMD, SPG2, HLD1
Protein Interaction Partner: CALR,CANX,ITGAV,MAG,MBP,MBP
Protein Size: 277 - Molecular Weight
- 30 kDa
- Gene ID
- 5354
- NCBI Accession
- NM_000533, NP_000524
- UniProt
- P60201
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