Polynucleotide Kinase 3'-Phosphatase (PNKP) (Middle Region) Peptide
PNKP
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PNKP products
- PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ALLSASPEVV VAVGFPGAGK STFLKKHLVS AGYVHVNRDT LGSWQRCVTT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PNKP Antibody(ARP52312_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))
- Synonyms
- EIEE10 Peptide, MCSZ Peptide, PNK Peptide, Tb06.28P18.320 Peptide, 21.m03011 Peptide, 1810009G08Rik Peptide, polynucleotide kinase 3'-phosphatase Peptide, hypothetical protein Peptide, polynucleotide kinase 3'- phosphatase Peptide, PNKP Peptide, Pnkp Peptide, Tc00.1047053507017.50 Peptide, Tc00.1047053505807.190 Peptide, Tb927.6.1580 Peptide, BBOV_IV000690 Peptide, CC1G_05202 Peptide, PGTG_20262 Peptide, PGTG_18987 Peptide, pnkp.S Peptide, pnkp Peptide
- Background
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This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.
Alias Symbols: PNK, MCSZ, EIEE10
Protein Interaction Partner: XRCC1,KRTAP4-12,MAGEA11,MYOZ1,SMAD5,TRIM37,XRCC1,XRCC4,ATAD3B,DDX20,HEATR2,KRTAP4-12,LAS1L,LIG3,LIG4,MAGEA11,MCM3,MYOZ1,NOL3,NOM1,NUP93,POLB,SLC25A12,TRIM37,XRCC1,XRCC4,YWHAQ
Protein Size: 521 - Molecular Weight
- 57 kDa
- Gene ID
- 11284
- NCBI Accession
- NM_007254, NP_009185
- UniProt
- Q96T60
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