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Cytohesin 4 (CYTH4) (N-Term) Peptide

CYTH4 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN982317
  • Target See all Cytohesin 4 (CYTH4) products
    Cytohesin 4 (CYTH4)
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 7
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PSCD4 antibody (Catalog #: ARP54947_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Cytohesin 4 (CYTH4)
    Synonyms
    zgc:175224 Peptide, CYT4 Peptide, DJ63G5.1 Peptide, PSCD4 Peptide, 2510004M07Rik Peptide, 5830469K17Rik Peptide, AI467541 Peptide, Pscd4 Peptide, mFLJ00017 Peptide, RGD1564842 Peptide, cytohesin-4 Peptide, cytohesin 4b Peptide, cytohesin 4 Peptide, cyth4b Peptide, CYTH4 Peptide, Cyth4 Peptide
    Background
    PSCD4 promotes guanine-nucleotide exchange on ARF1 and ARF5. PSCD4 promotes the activation of ARF through replacement of GDP with GTP.Pleckstrin homology, Sec7 and coiled/coil domains 4 (PSCD4) is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The PSCD4 exhibits GEP activity in vitro with both ARF1 and ARF5 but is inactive with ARF6. The PSCD4 and PSCD1 gene structures are very similar.

    Alias Symbols: CYT4, DJ63G5.1, PSCD4

    Protein Interaction Partner: IPCEF1

    Protein Size: 394
    Molecular Weight
    46 kDa
    Gene ID
    27128
    NCBI Accession
    NM_013385, NP_037517
    UniProt
    Q9UIA0
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