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Presenilin 1 (PSEN1) (N-Term) Peptide

PSEN1 Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN982320
  • Target See all Presenilin 1 (PSEN1) products
    Presenilin 1 (PSEN1)
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 8
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PSEN1 antibody (Catalog #: ARP44201_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Presenilin 1 (PSEN1)
    Synonyms
    pre1 Peptide, psen Peptide, zfPS1 Peptide, zf-PS1 Peptide, ad3 Peptide, fad Peptide, ps1 Peptide, s182 Peptide, X-PS-beta Peptide, X-PS-alpha Peptide, AD3 Peptide, FAD Peptide, PS-1 Peptide, PS1 Peptide, S182 Peptide, Ad3h Peptide, presenilin 1 Peptide, presenilin 1 L homeolog Peptide, psen1 Peptide, PSEN1 Peptide, Psen1 Peptide, psen1.L Peptide
    Background
    Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1, PSEN2) or in the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form o

    Alias Symbols: AD3, FAD, PS1, S182, PS-1

    Protein Interaction Partner: APH1A,APP,APP,APP,APP,CTNNB1,CTNND2,NCSTN,STX1A,STX5,CASP1,CASP3,CASP4,CASP7,APBA1,APH1A,APH1B,APP,BACE1,BCL2,BCL2L1,CASP1,CASP3,CASP4,CASP6,CASP7,CASP8,CDH1,CDK5,CIB1,CTNNA1,CTNNB1,CTNND1,CTNND2,DLL1,DOCK3,EFNB2,ERN1,FBXW7,FLNA,FLNB,GDI1,GFAP,GSK3B,HERPUD1,ICAM5,JUP,KCNIP3,MAPT,METTL2A,MTCH1,NCSTN,NOTCH1,NOTCH2,NOTCH3,NOTCH4,PIK3R1,PKP4,PRKACA,PRKCZ,PSEN1,PSENEN,RAB11A,SRSF2IP,TCF7L2,UBQLN1,YME1L1,APH1A,APP,BCL2,BCL2L1,CDH1,CIB1,CLSTN1,CTNNA1,CTNNB1,CTNND1,Ctnnb1,ERN1,FBXW7,FLNB,GFAP,GSK3B,HERPUD1,ICAM5,KCNIP3,KCNIP4,MAPT,NCSTN,NOTCH1,PKP4,PSEN1,PSEN2,PSENEN,PSENEN,TCF7L2,TRAF6,UBQLN1,YME1L1

    Protein Size: 467
    Molecular Weight
    53 kDa
    Gene ID
    5663
    NCBI Accession
    NM_000021, NP_000012
    UniProt
    P49768
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