Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11) Peptide
PSMD11
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN982376
$160.46
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100 μg
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Quick Overview for Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11) Peptide (ABIN982376)
Target
PSMD11
(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PSMD11 antibody (Catalog #: ARP33002_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PSMD11 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))
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Background
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator.
Alias Symbols: S9, Rpn6, p44.5
Protein Interaction Partner: BRD7,C1orf103,C7orf64,CCDC90B,COPS6,CRMP1,EEF1A1,EEF1G,FAM190B,GAPDH,GDF9,HAP1,IGSF21,MED31,NFKB2,PTN,PTPRK,SETDB1,SMAD1,SMAD2,SMAD3,SMAD4,SMAD5,TLE1,TP53,UNC119,ZBTB16,ZHX1,BRD7,C1orf103,C7orf64,CCDC90B,COPS6,CRMP1,EEF1A1,EEF1G,FAM190B,GAPDH,GDF9,GIYD2,HAP1,IGSF21,MED31,PAAF1,PSMC4,PSMD10,PSMD13,PSMD14,PSMD6,PSMD7,PTN,PTPRK,SETDB1,TLE1,TP53,TUBB2A,UCHL5,UNC119,USP14,USP15,USP20,ZBTB16,ZHX1
Protein Size: 422 -
Molecular Weight
- 47 kDa
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Gene ID
- 5717
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NCBI Accession
- NM_002815, NP_002806
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UniProt
- O00231
Target
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