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Purine-Rich Element Binding Protein A (PURA) (N-Term) Peptide

PURA Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN982476
  • Target See all PURA products
    PURA (Purine-Rich Element Binding Protein A (PURA))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    MADRDSGSEQ GGAALGSGGS LGHPGSGSGS GGGGGGGGGG GGSGGGGGGA
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- PURA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PURA (Purine-Rich Element Binding Protein A (PURA))
    Synonyms
    CAGER-1 Peptide, Pur-alpha Peptide, ssCRE-BP Peptide, PUR-ALPHA Peptide, PUR1 Peptide, PURALPHA Peptide, zgc:103411 Peptide, pur-alpha Peptide, pur1 Peptide, puralpha Peptide, purine-rich element binding protein A Peptide, purine rich element binding protein A Peptide, purine-rich element binding protein Aa Peptide, purine-rich element binding protein A L homeolog Peptide, pura Peptide, Pura Peptide, PURA Peptide, puraa Peptide, pura.L Peptide
    Background
    This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.

    Alias Symbols: PUR1, MRD31, PURALPHA, PUR-ALPHA

    Protein Size: 322
    Molecular Weight
    35 kDa
    Gene ID
    5813
    NCBI Accession
    NM_005859, NP_005850
    UniProt
    Q00577
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