Purine-Rich Element Binding Protein A (PURA) (Middle Region) Peptide
PURA
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN982477
Quick Overview for Purine-Rich Element Binding Protein A (PURA) (Middle Region) Peptide (ABIN982477)
Target
PURA
(Purine-Rich Element Binding Protein A (PURA))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PURA antibody (Catalog #: ARP33202_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PURA (Purine-Rich Element Binding Protein A (PURA))
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Background
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PURA is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PUR-ALPHA, PUR1, PURALPHA
Protein Interaction Partner: Jvgp5,YBX1,ADAP1,CCNT1,CDK5,E2F1,PURB,RB1,SP1,YBX1,CCNT1,CNBP,E2F1,HNRNPA1,MEPCE,SP1
Protein Size: 322 -
Molecular Weight
- 35 kDa
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Gene ID
- 5813
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NCBI Accession
- NM_005859, NP_005850
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UniProt
- Q00577
Target
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