Cell Cycle Checkpoint Protein RAD1 (RAD1) (Middle Region) Peptide
RAD1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RAD1 products
- RAD1 (Cell Cycle Checkpoint Protein RAD1 (RAD1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ITMSPDKPYF RLSTFGNAGS SHLDYPKDSD LMEAFHCNQT QVNRYKISLL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RAD1 Antibody(ARP57717_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RAD1 (Cell Cycle Checkpoint Protein RAD1 (RAD1))
- Synonyms
- HRAD1 Peptide, REC1 Peptide, zgc:56502 Peptide, zgc:77779 Peptide, RAD1 Peptide, xrad1 Peptide, DKFZp459H1127 Peptide, RAD1 checkpoint DNA exonuclease Peptide, RAD1 homolog (S. pombe) Peptide, RAD1 Peptide, Rad1 Peptide, rad1 Peptide
- Background
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This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described.
Alias Symbols: HRAD1, REC1
Protein Interaction Partner: DNAJC7,FEN1,HUS1,HUS1B,MAP1LC3B,PARK2,POLB,RAD17,RAD9B,DNAJC7,DNAJC7,FEN1,HUS1,HUS1B,PARK2,RAD17,RAD9A,RAD9B,RPA1,RPA2,RPA2
Protein Size: 282 - Molecular Weight
- 32 kDa
- Gene ID
- 5810
- NCBI Accession
- NM_002853, NP_002844
- UniProt
- O60671
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