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RAD23 Homolog A (RAD23A) Peptide

RAD23A Reactivity: Human Host: Synthetic BP, IHC, WB
Catalog No. ABIN982604
  • Target See all RAD23A products
    RAD23A (RAD23 Homolog A (RAD23A))
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-RAD23A antibody (Catalog #: ARP42210_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    RAD23A (RAD23 Homolog A (RAD23A))
    Synonyms
    rad23a Peptide, wu:fe11h06 Peptide, zgc:92001 Peptide, RAD23A Peptide, HHR23A Peptide, HR23A Peptide, 2310040P19Rik Peptide, AL024030 Peptide, mHR23A Peptide, RAD23 homolog A, nucleotide excision repair protein a Peptide, RAD23 homolog A, nucleotide excision repair protein Peptide, rad23aa Peptide, RAD23A Peptide, Rad23a Peptide
    Background
    RAD23A is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

    Alias Symbols: HHR23A, MGC111083

    Protein Interaction Partner: ATXN3,EP300,ATXN3,ATXN7,EP300,EWSR1,MPG,PDE6D,PSMD4,RPN1,SQSTM1,TRAF2,UBB,UBL7,UBQLN4,XPC,ATXN3,EWSR1,OTUD1,PDE6D,PSMD4,SQSTM1,TRAF2,UBI4,UBL7,XPC

    Protein Size: 363
    Molecular Weight
    40 kDa
    Gene ID
    5886
    NCBI Accession
    NM_005053, NP_005044
    UniProt
    P54725
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