Replication Factor C (Activator 1) 3, 38kDa (RFC3) Peptide
RFC3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RFC3 products
- RFC3 (Replication Factor C (Activator 1) 3, 38kDa (RFC3))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RFC3 antibody (Catalog #: ARP46084_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RFC3 (Replication Factor C (Activator 1) 3, 38kDa (RFC3))
- Synonyms
- CG5313 Peptide, DRFC Peptide, DmRFC3 Peptide, Dmel\\CG5313 Peptide, Rfc3 Peptide, 21.m02902 Peptide, 2810416I22Rik Peptide, 38kDa Peptide, AU022547 Peptide, Recc3 Peptide, cb275 Peptide, RFC38 Peptide, Replication factor C subunit 3 Peptide, replication factor C3 Peptide, replication factor C subunit 3 Peptide, replication factor C 38 kDa subunit Peptide, DNA replication factor C complex subunit Rfc3 Peptide, replication factor C3, putative Peptide, replication factor C (activator 1) 3 Peptide, replication factor C subunit 3 L homeolog Peptide, RfC3 Peptide, PF14_0601 Peptide, Chro.30359 Peptide, PB000006.01.0 Peptide, PC000345.04.0 Peptide, TP04_0380 Peptide, Tb09.211.3310 Peptide, PY04255 Peptide, PVX_117300 Peptide, BBOV_IV003080 Peptide, SJAG_02182 Peptide, PKH_124240 Peptide, rfc3 Peptide, Rfc3 Peptide, RFC3 Peptide, rfc3.L Peptide
- Background
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The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. RFC3 is the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Alias Symbols: MGC5276, RFC38
Protein Interaction Partner: PCNA,CHTF8,PCNA,RFC1,RFC4,BRD4,CHTF18,MEPCE,PCNA,RAD17,RFC1,RFC4,USP20
Protein Size: 356 - Molecular Weight
- 40 kDa
- Gene ID
- 5983
- NCBI Accession
- NM_002915, NP_002906
- UniProt
- P40938
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