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Ring Finger and FYVE-Like Domain Containing 1 (RFFL) (Middle Region) Peptide

RFFL Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN982872
  • Target See all RFFL products
    RFFL (Ring Finger and FYVE-Like Domain Containing 1 (RFFL))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    KDQKGLQHLV SGAEDQNGGA VPSGLEENLC KICMDSPIDC VLLECGHMVT
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-RFFL Antibody(ARP42986_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    RFFL (Ring Finger and FYVE-Like Domain Containing 1 (RFFL))
    Synonyms
    MGC84042 Peptide, RFFL Peptide, Rffl Peptide, 1700051E09Rik Peptide, 4930516L10Rik Peptide, BG080975 Peptide, Carp2 Peptide, CARP-2 Peptide, CARP2 Peptide, FRING Peptide, RIFIFYLIN Peptide, RNF189 Peptide, RNF34L Peptide, ring finger and FYVE like domain containing E3 ubiquitin protein ligase Peptide, ring finger and FYVE-like domain containing E3 ubiquitin protein ligase L homeolog Peptide, ring finger and FYVE-like domain containing 1 Peptide, ring finger and FYVE like domain containing protein Peptide, ring finger and FYVE-like domain containing E3 ubiquitin protein ligase Peptide, RFFL Peptide, rffl.L Peptide, Rffl Peptide
    Background
    RFFL has E3 ubiquitin protein ligase activity.RFFL regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity.RFFL may bind phosphatidylinositol phosphates.

    Alias Symbols: RNF189, RNF34L, CARP2, FRING, CARP-2, RIFIFYLIN

    Protein Interaction Partner: UBE2G2

    Protein Size: 363
    Molecular Weight
    40 kDa
    Gene ID
    117584
    NCBI Accession
    NM_001017368, NP_001017368
    UniProt
    Q8WZ73
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