Translocation Protein 1 (TLOC1) (Middle Region) Peptide
TLOC1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SEC62 (TLOC1) products
- SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))
- Protein Region
- Middle Region
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KYDKDIKKEK DKGKAESGKE EDKKSKKENI KDEKTKKEKE KKKDGEKEES
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SEC62 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))
- Synonyms
- tloc1 Peptide, TLOC1 Peptide, wu:fb57b06 Peptide, zgc:114073 Peptide, Dtrp1 Peptide, HTP1 Peptide, TP-1 Peptide, 3100002M17Rik Peptide, AI844545 Peptide, AW545092 Peptide, Tloc1 Peptide, Ab2-292 Peptide, SEC62 homolog, preprotein translocation factor S homeolog Peptide, SEC62 homolog, preprotein translocation factor Peptide, membrane unit of ER protein translocation apparatus Peptide, SEC62 homolog (S. cerevisiae) Peptide, sec62.S Peptide, SEC62 Peptide, sec62 Peptide, Sec62 Peptide
- Background
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The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.
Alias Symbols: Dtrp1, FLJ32803, HTP1, TLOC1, TP-1
Protein Interaction Partner: CIC,SEC63
Protein Size: 399 - Molecular Weight
- 46 kDa
- Gene ID
- 7095
- NCBI Accession
- NM_003262, NP_003253
- UniProt
- Q99442
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