SECIS Binding Protein 2 (SECISBP2) (N-Term) Peptide
SECISBP2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SECISBP2 products
- SECISBP2 (SECIS Binding Protein 2 (SECISBP2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- FDSERADGTI SSEIKSARGS HHLSIYAENS LKSDGYHKRT DRKSRIIAKN
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SECISBP2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SECISBP2 (SECIS Binding Protein 2 (SECISBP2))
- Synonyms
- SBP2 Peptide, 2210413N07Rik Peptide, 2810012K13Rik Peptide, CG7066 Peptide, Dmel\\CG7066 Peptide, DKFZp459F1026 Peptide, Sbp2 Peptide, SECIS binding protein 2 Peptide, SECIS-binding protein 2 Peptide, Secisbp2 Peptide, Sbp2 Peptide, SECISBP2 Peptide, secisbp2 Peptide
- Background
-
The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism.
Alias Symbols: DKFZp686C09169, SBP2
Protein Interaction Partner: ATXN7L3,SMAD9
Protein Size: 854 - Molecular Weight
- 95 kDa
- Gene ID
- 79048
- NCBI Accession
- NM_024077, NP_076982
- UniProt
- Q96T21
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