Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) Peptide
SPI1
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN983634
Quick Overview for Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) Peptide (ABIN983634)
Target
SPI1
(Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))
Origin
Human, Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SFPI1 antibody (Catalog #: ARP37890_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))
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Background
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Sfpi1 binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. Sfpi1 is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Sfpi1 also binds RNA and may modulate pre-mRNA splicing.
Alias Symbols: Dis1, PU.1, Spi1, Dis-1, Spi-1, Sfpi-1, Tcfpu1, Tfpu.1, SFPI1
Protein Interaction Partner: Crebbp,Csf1r,Gata3,Id2,Il7r
Protein Size: 272 -
Molecular Weight
- 30 kDa
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Gene ID
- 20375
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NCBI Accession
- NM_011355, NP_035485
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UniProt
- P17433
Target
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