Premelanosome Protein (PMEL) Peptide
PMEL
Reactivity: Human
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN983749
Quick Overview for Premelanosome Protein (PMEL) Peptide (ABIN983749)
Target
Melanoma gp100 (PMEL)
(Premelanosome Protein (PMEL))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SILV antibody (Catalog #: ARP46802_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
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Background
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SILV could be a melanogenic enzyme. It could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, it could protect tumor cells from antibody mediated immunity.
Alias Symbols: D12S53E, ME20, PMEL17, SI, SIL, gp100, P1, P100, SILV, ME20M, ME20-M
Protein Size: 661 -
Molecular Weight
- 70 kDa
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Gene ID
- 6490
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NCBI Accession
- NM_006928, NP_008859
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UniProt
- P40967
Target
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