Premelanosome Protein (PMEL) Peptide
PMEL
Reactivity: Mammalian
Host: Synthetic
BP, IHC, WB
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- Target See all Melanoma gp100 (PMEL) products
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Sequence
- HFLRNQPLTF ALQLHDPSGY LAEADLSYTW DFGDSSGTLI SRALVVTHTY
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SILV antibody,
Alternative Names: SILV control peptide, SILV antibody Blocking Peptide, Anti-SILV Blocking Peptide, Silver Homolog Blocking Peptide, D12S53E Blocking Peptide, ME20 Blocking Peptide, PMEL17 Blocking Peptide, SI Blocking Peptide, SIL Blocking Peptide, gp100 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
- Synonyms
- D12S53E Peptide, ME20 Peptide, ME20-M Peptide, ME20M Peptide, P1 Peptide, P100 Peptide, PMEL17 Peptide, SI Peptide, SIL Peptide, SILV Peptide, gp100 Peptide, D10H12S53E Peptide, D12S53Eh Peptide, Pmel17 Peptide, Si Peptide, Silv Peptide, gp87 Peptide, RPE1 Peptide, MMP115 Peptide, silverb Peptide, silver Peptide, cb397 Peptide, fdv Peptide, pmel17 Peptide, sb:cb397 Peptide, silva Peptide, wu:fc11g11 Peptide, wu:fj24g11 Peptide, zgc:136622 Peptide, premelanosome protein Peptide, premelanosome protein b Peptide, premelanosome protein a Peptide, PMEL Peptide, Pmel Peptide, pmelb Peptide, pmela Peptide
- Background
- SILV could be a melanogenic enzyme. It could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, it could protect tumor cells from antibody mediated immunity.
- Molecular Weight
- 70 kDa
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