Snurportin 1 (SNUPN) (Middle Region) Peptide
SNUPN
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Snurportin 1 (SNUPN) products
- Snurportin 1 (SNUPN)
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SNUPN antibody (Catalog #: ARP40598_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Snurportin 1 (SNUPN)
- Synonyms
- rnut1 Peptide, zgc:77819 Peptide, wu:fc41a03 Peptide, SNUPN Peptide, kpnbl Peptide, snurportin1 Peptide, KPNBL Peptide, RNUT1 Peptide, Snurportin1 Peptide, 0610031A09Rik Peptide, Rnut1 Peptide, Snupn1 Peptide, snurportin 1 Peptide, snupn Peptide, SNUPN Peptide, Snupn Peptide
- Background
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The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. SNUPN interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor.The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: KPNBL, RNUT1, Snurportin1
Protein Interaction Partner: ENO2,KPNB1,PAFAH1B2,PEX5,RPL17,TNNT3,XPO1,DDX20,ENO2,KPNB1,PEX5,RAN,SMN1,SNRPB,TNNT3,XPO1,ZNF259
Protein Size: 360 - Molecular Weight
- 41 kDa
- Gene ID
- 10073
- NCBI Accession
- NM_005701, NP_005692
- UniProt
- O95149
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