Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) Peptide
SPI1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984340
Quick Overview for Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) Peptide (ABIN984340)
Target
SPI1
(Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SPI1 antibody (Catalog #: ARP31421_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))
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Background
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SPI1 is known to collaborate with multiple transcription factors and to regulate expression of immunoglobulin genes. Lack of SPI1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease
Alias Symbols: OF, PU.1, SFPI1, SPI-1, SPI-A
Protein Interaction Partner: CEBPE,GATA1,PRG2,ATF1,CEBPA,CEBPB,CEBPD,CEBPE,CREBBP,CREM,ERG,FUS,GATA1,GATA2,IRF4,IRF8,JUN,MITF,MYST3,NFATC1,NFKB1,NONO,PIP,RB1,SPIB,SSRP1,TBP,ATF1,CEBPA,CEBPB,CREM,CSNK2A1,DNMT3A,DNMT3B,ETS1,ETS2,ETV1,FOS,FUS,GATA2,HDAC1,IRF4,JUN,MAPK8,MECP2,MITF,NFYA,NONO,SPIB
Protein Size: 264 -
Molecular Weight
- 30 kDa
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Gene ID
- 6688
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NCBI Accession
- NM_003120, NP_003111
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UniProt
- P17947
Target
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