Sepiapterin Reductase (SPR) (C-Term) Peptide
SPR
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984373
Quick Overview for Sepiapterin Reductase (SPR) (C-Term) Peptide (ABIN984373)
Target
SPR
(Sepiapterin Reductase (SPR))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- ETSVDPDMRK GLQELKAKGK LVDCKVSAQK LLSLLEKDEF KSGAHVDFYD
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SPR Antibody(ARP59628_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SPR (Sepiapterin Reductase (SPR))
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Background
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This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
Alias Symbols: SDR38C1
Protein Interaction Partner: CAMK2G
Protein Size: 261 -
Molecular Weight
- 28 kDa
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Gene ID
- 6697
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NCBI Accession
- NM_003124, NP_003115
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UniProt
- P35270
Target
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