Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (Middle Region) Peptide
Quick Overview for Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (Middle Region) Peptide (ABIN984527)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-STAT3 antibody (Catalog #: ARP30317_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- STAT3 (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
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Background
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STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act a
Alias Symbols: APRF, FLJ20882, MGC16063, HIES
Protein Interaction Partner: NMI,BHLHE40,CREBBP,EGFR,EP300,HDAC1,HDAC2,HDAC3,NMI,PRKCB,PRKCD,STAT3,BHLHE40,AR,BHLHE40,BMX,BRCA1,CCND1,CCR1,CCR5,CDKN1A,CREBBP,CSF2RB,CSF3R,CXCR4,DAXX,EGFR,EIF2AK2,ELP2,EP300,EPHA3,FER,FES,FGFR3,FGFR4,FOXM1,GATA1,GATA2,GHR,GNB2L1,GTF2I,HCK,HDAC1,HDAC2,HDAC3,HES1,HES5,HIF1A,HNF1A,HSP90AA1,HSP90AB1,IFNAR1,IFNAR2,IGF1R,IL1RAP,IL23R,IL2RA,IL2RB,IL6R,IL6ST,IL7R,IRAK1,JAK1,JAK2,JAK3,JUN,KAT5,KHDRBS1,KPNA1,KPNA6,LCK,LEPR,MAP3K7,MAPK1,MAPK3,MAPK8,MET,MTOR,MYOD1,NCOA1,NDUFA13,NFKB1,NLK,NMI,NR3C1,PDGFRA,PDGFRB,PDIA3,PIAS3,PML,PRKCD,PTK2B,PTMA,PTPN11,PTPN2,RAC1,RELA,RET,RPA2,RPS6KA5,SRC,STAP2,STAT1,STAT3,STAT4,STAT5A,STAT5B,STMN1,SUMO4,SYK,TSHR,TSLP,ZNF148,ZNF467,A2M,ALK,AR,BMX,CCND1,CCND1,CCR5,CDKN1A,CREBBP,CTR9,EGFR,EIF2AK2,ELP2,EP300,EPHA5,ERBB2,ESR1,FES,FOS,GHR,GTF2I,HIF1A,HNF1A,HSP90AA1,IFNAR1,IL1RAP,IL2RB,IL6R,IL6ST,IL6ST,JAK1,JAK2,JUN,KAT5,KHDRBS1,LEP,MET,MTOR,MYOD1,NCOA1,NDUFA13,NDUFA13,NFKB1,NMI,NR3C1,PDIA3,PIAS3,PML,PTK2,PTPN11,PTPN2,RAC1,RELA,RET,RPA2,SMAD1,SRC,STAT1,TRIP10,TSHR
Protein Size: 770 -
Molecular Weight
- 88 kDa
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Gene ID
- 6774
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NCBI Accession
- NM_139276, NP_644805
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UniProt
- P40763
Target
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