Small Ubiquitin Related Modifier 3 (SUMO3) (N-Term) Peptide
SUMO3
Reactivity: Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN984626
$160.46
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 11 to 17 Business Days
Quick Overview for Small Ubiquitin Related Modifier 3 (SUMO3) (N-Term) Peptide (ABIN984626)
Target
SUMO3
(Small Ubiquitin Related Modifier 3 (SUMO3))
Origin
Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Sequence
- DQEAKPSTED LGDKKEGEYI KLKVIGQDSS EIHFKVKMTT HLKKLKESYC
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-Sumo1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- SUMO3 (Small Ubiquitin Related Modifier 3 (SUMO3))
-
Background
-
Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. It is involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. It may also regulate a network of genes involved in palate development.
Alias Symbols: GMP1, MGC103203, PIC1, SENTRIN, SMT3, SMT3H3, SMTP3, SUMO-1, Smt3C, Ubl1
Protein Interaction Partner: Jun,Junb,Hif1a,Nfkb2,Pou5f1
Protein Size: 101 -
Molecular Weight
- 11 kDa
-
Gene ID
- 22218
-
NCBI Accession
- NM_009460, NP_033486
-
UniProt
- P63166
Target
-
You are here:
