FACT complex subunit SPT16 (SUPT16H) Peptide
SUPT16H
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984630
Quick Overview for FACT complex subunit SPT16 (SUPT16H) Peptide (ABIN984630)
Target
SUPT16H
(FACT complex subunit SPT16 (SUPT16H))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SUPT16H antibody (Catalog #: ARP31526_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SUPT16H (FACT complex subunit SPT16 (SUPT16H))
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Background
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Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit, the latter of which is SUPT16H.
Alias Symbols: CDC68, FACT, FACTP140, FLJ10857, FLJ14010, FLJ34357, SPT16/CDC68
Protein Interaction Partner: H3F3A,HES1,GTF2E2,H3F3B,MCM3,MCM4,NEK9,SFRS12,BAZ1B,BRCC3,HIST2H2BE
Protein Size: 602 -
Molecular Weight
- 66 kDa
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Gene ID
- 11198
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NCBI Accession
- NM_007192
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UniProt
- Q9Y5B9
Target
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