Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) (C-Term) Peptide
SYNGAP1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SYNGAP1 products
- SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EYKLKEYSKS MDESRLDRVK EYEEEIHSLK ERLHMSNRKL EEYERRLLSQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SYNGAP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))
- Synonyms
- SYNGAP1 Peptide, Syngap Peptide, MRD5 Peptide, RASA1 Peptide, RASA5 Peptide, SYNGAP Peptide, Gm1963 Peptide, synaptic Ras GTPase activating protein 1 Peptide, zinc finger and BTB domain containing 9 Peptide, synaptic Ras GTPase activating protein 1 homolog (rat) Peptide, SYNGAP1 Peptide, ZBTB9 Peptide, syngap1 Peptide, Syngap1 Peptide
- Background
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The protein encoded by this gene is a major component of the postsynaptic density (PSD), a group of proteins found associated with NMDA receptors at synapses. The encoded protein is phosphorylated by calmodulin-dependent protein kinase II and dephosphorylated by NMDA receptor activation. Defects in this gene are a cause of mental retardation autosomal dominant type 5 (MRD5).
Alias Symbols: DKFZp761G1421, KIAA1938, MRD5, RASA1, RASA5, SYNGAP
Protein Size: 1343 - Molecular Weight
- 148 kDa
- Gene ID
- 8831
- NCBI Accession
- NM_006772, NP_006763
- UniProt
- Q96PV0
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