Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (N-Term) Peptide
TCF7L2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TCF7L2 products
- TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TCF7L2 antibody (Catalog #: ARP33413_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
- Synonyms
- TCF4B Peptide, TCF4E Peptide, Tcf-4 Peptide, Tcf4 Peptide, mTcf-4B Peptide, mTcf-4E Peptide, tcf4 Peptide, XTCF-4 Peptide, tcf4e Peptide, TCF4 Peptide, TCF-4 Peptide, TCFL2 Peptide, transcription factor 7 like 2 Peptide, transcription factor 7-like 2 Peptide, transcription factor 7 like 2, T cell specific, HMG box Peptide, transcription factor 7 like 2 L homeolog Peptide, transcription factor 7-like 2 (T-cell specific, HMG-box) Peptide, TCF7L2 Peptide, LOC100545943 Peptide, Tcf7l2 Peptide, tcf7l2 Peptide, tcf7l2.L Peptide
- Background
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The TCL7L2 is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. suggested that TCL7L2 acts through regulation of proglucagon through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway. The TCL7L2 gene product is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. (2005) [PubMed 15525634] suggested that TCL7L2 acts through regulation of proglucagon (MIM 138030) through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway.[supplied by OMIM]. Sequence Note: This gene (TCF7L2, alias TCF-4) is distinct from TCF4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-202 DA473655.1 1-202 203-251 Y11306.2 3-51 252-1252 AK225809.1 256-1256 1253-1305 Y11306.2 1053-1105 1306-1756 AK225809.1 1310-1760 1757-1811 Y11306.2 1557-1611 1812-2652 AK225809.1 1765-2605
Alias Symbols: TCF-4, TCF4
Protein Interaction Partner: CTBP1,CTNNB1,CTNNB1,RAC1,CSNK2A1,CSNK2A2,CTNNB1,CTNNBIP1,DAXX,EP300,JUP,PSEN1,CTNNB1,JUP,NLK,PSEN1
Protein Size: 596 - Molecular Weight
- 65 kDa
- Gene ID
- 6934
- NCBI Accession
- NM_030756, NP_110383
- UniProt
- Q6FHW4
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