Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (N-Term) Peptide
TCF7L2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984910
Quick Overview for Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (N-Term) Peptide (ABIN984910)
Target
TCF7L2
(Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- MPQLNGGGGD DLGANDELIS FKDEGEQEEK SSENSSAERD LADVKSSLVN
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- TCF7L2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
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Background
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This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.
Alias Symbols: TCF4, TCF-4
Protein Size: 619 -
Molecular Weight
- 51 kDa
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Gene ID
- 6934
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NCBI Accession
- XM_005270084, XP_005270141
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UniProt
- Q9NQB0
Target
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