Testis Derived Transcript (3 LIM Domains) (TES) (Middle Region) Peptide
TES
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984960
$160.46
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100 μg
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Quick Overview for Testis Derived Transcript (3 LIM Domains) (TES) (Middle Region) Peptide (ABIN984960)
Target
TES
(Testis Derived Transcript (3 LIM Domains) (TES))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- PKQMNIPGGD RSTPAAVGAM EDKSAEHKRT QYSCYCCKLS MKEGDPAIYA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TES Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TES (Testis Derived Transcript (3 LIM Domains) (TES))
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Background
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Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.
Alias Symbols: DKFZp586B2022, MGC1146, TESS, TESS-2
Protein Interaction Partner: ACTL7A,ENAH,EVL,GRIP1,SPTAN1,TES,TLN1,VASP,ACTL7A,ACTN1,ENAH,EVL,GRIPAP1,SPOCK2,SPTAN1,TES,TLN1,VASP,ZYX,ACTA1,ENAH,RAB8B,VASP,ZYX
Protein Size: 421 -
Molecular Weight
- 46 kDa
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Gene ID
- 26136
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NCBI Accession
- NM_015641, NP_056456
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UniProt
- Q9UGI8
Target
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