Transcription Factor EB (TFEB) Peptide
Quick Overview for Transcription Factor EB (TFEB) Peptide (ABIN985006)
Target
Origin
Source
Application
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TFEB antibody (Catalog #: ARP38810_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TFEB (Transcription Factor EB (TFEB))
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Background
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TFEB is a member of the basic Helix-Loop-Helix-Zipper family of transcription factors. TFEB can bind DNA as a homodimer or as a heterodimer with three closely related family members: MITF, TFE3 and TFEC. The t(6,11)(p21,q12), a translocation recently been shown to result in fusion of Alpha, a gene on 11q12, with the transcription factor gene TFEB on 6p21.This translocation ultimately leads to the development of Renal carcinomas.
Alias Symbols: TCFEB, BHLHE35, ALPHATFEB
Protein Interaction Partner: MITF,TFE3,TFEC
Protein Size: 476 -
Molecular Weight
- 53 kDa
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Gene ID
- 7942
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NCBI Accession
- NM_007162, NP_009093
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UniProt
- P19484
Target
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