Exoribonuclease 1 (ERI1) Peptide
ERI1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ERI1 products
- ERI1 (Exoribonuclease 1 (ERI1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-THEX1 antibody (Catalog #: ARP41158_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ERI1 (Exoribonuclease 1 (ERI1))
- Background
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THEX1 contains 1 SAP domain and 1 exonuclease domain. It is an RNA exonuclease that binds to the 3' end of histone mRNAs and probably degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. It is also able to degrade the 3' overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi).
Alias Symbols: HEXO, THEX1, 3'HEXO
Protein Interaction Partner: SLBP
Protein Size: 349 - Molecular Weight
- 38 kDa
- Gene ID
- 90459
- NCBI Accession
- NM_153332, NP_699163
- UniProt
- Q8IV48
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