Transmembrane Emp24-Like Trafficking Protein 10 (TMED10) (Middle Region) Peptide
TMED10
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TMED10 products
- TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TMED10 antibody (Catalog #: ARP58728_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
- Synonyms
- tmp21 Peptide, P24(DELTA) Peptide, S31I125 Peptide, S31III125 Peptide, TMP21 Peptide, Tmp-21-I Peptide, p23 Peptide, 1110014C03Rik Peptide, Tmp21 Peptide, p24delta1 Peptide, fe06g04 Peptide, wu:fb98e10 Peptide, wu:fe06g04 Peptide, zgc:85681 Peptide, transmembrane p24 trafficking protein 10 L homeolog Peptide, transmembrane p24 trafficking protein 10 Peptide, tmed10.L Peptide, TMED10 Peptide, Tmed10 Peptide, tmed10 Peptide
- Background
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TMED10 is involved in vesicular protein trafficking.This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Alias Symbols: P24(DELTA), S31I125, S31III125, TMP21, Tmp-21-I, p23
Protein Interaction Partner: APH1A,ARF1,NCSTN,PSENEN,TMED2,GORASP2
Protein Size: 219 - Molecular Weight
- 24 kDa
- Gene ID
- 10972
- NCBI Accession
- NM_006827, NP_006818
- UniProt
- P49755
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