Transmembrane Protease, serine 6 (TMPRSS6) (N-Term) Peptide
TMPRSS6
Reactivity: Human
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN985287
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for Transmembrane Protease, serine 6 (TMPRSS6) (N-Term) Peptide (ABIN985287)
Target
TMPRSS6
(Transmembrane Protease, serine 6 (TMPRSS6))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TMPRSS6 antibody (Catalog #: ARP53188_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))
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Background
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TMPRSS6 is a serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. TMPRSS6 can also activate urokinase-type plasminogen activator with low efficiency. TMPRSS6 may play a specialized role in matrix remodeling processes in liver. TMPRSS6 is required to sense iron deficiency. Overexpression of TMPRSS6 suppresses activation of the HAMP promoter.The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver.
Alias Symbols: IRIDA
Protein Interaction Partner: COL1A1,FN1,LAMA1
Protein Size: 811 -
Molecular Weight
- 90 kDa
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Gene ID
- 164656
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NCBI Accession
- NM_153609, NP_705837
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UniProt
- Q8IU80
Target
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