Cardiac Troponin I (TNNI3) Peptide
TNNI3
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all TNNI3 products
- TNNI3 (Cardiac Troponin I (TNNI3))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TNNI3 antibody (Catalog #: ARP41391_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TNNI3 (Cardiac Troponin I (TNNI3))
- Synonyms
- CMD1FF Peptide, CMD2A Peptide, CMH7 Peptide, RCM1 Peptide, TNNC1 Peptide, cTnI Peptide, CMD1Z Peptide, CMH13 Peptide, TN-C Peptide, TNC Peptide, TNNC Peptide, Tn1 Peptide, TnIc Peptide, ctnIc Peptide, XTnIc Peptide, c-troponin Peptide, cTNT Peptide, cmh7 Peptide, ctni Peptide, tnnc1 Peptide, TNNI3 Peptide, TnI Peptide, cTNI Peptide, AI874626 Peptide, TnC Peptide, cTnC Peptide, tncc Peptide, Tncc Peptide, troponin I3, cardiac type Peptide, troponin C1, slow skeletal and cardiac type Peptide, troponin I, cardiac 3 Peptide, troponin I type 3 (cardiac) Peptide, troponin I3, cardiac type S homeolog Peptide, troponin I3, cardiac type L homeolog Peptide, cardiac troponin I Peptide, troponin C, cardiac/slow skeletal Peptide, TNNI3 Peptide, TNNC1 Peptide, Tnni3 Peptide, tnni3.S Peptide, tnni3.L Peptide, tnni3 Peptide, LOC100462680 Peptide, Tnnc1 Peptide
- Background
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Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. TNNI3 is the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues.Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMH7, MGC116817, TNNC1, cTnI, RCM1, CMD2A, CMD1FF
Protein Interaction Partner: ACTA1,PAPPA,PKD2,PKD2L1,PRKCA,RCAN3,TNNC1,TNNI3,TNNI3K,TNNT1,TNNT2,LYST,PKD2,PKD2L1,TNNC1,TNNI3K,TNNT2
Protein Size: 210 - Molecular Weight
- 23 kDa
- Gene ID
- 7137
- NCBI Accession
- NM_000363, NP_000354
- UniProt
- Q59H18
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