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Tribbles Homolog 3 (Drosophila) (TRIB3) (N-Term) Peptide

TRIB3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN985472
  • Target See all TRIB3 products
    TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    YVLLEPEEGG RAYQALHCPT GTEYTCKVYP VQEALAVLEP YARLPPHKHV
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-TRIB3 Antibody(ARP57518_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
    Synonyms
    zgc:76966 Peptide, TRIB3 Peptide, C20orf97 Peptide, NIPK Peptide, SINK Peptide, SKIP3 Peptide, TRB3 Peptide, Ifld2 Peptide, Nipk Peptide, TRB-3 Peptide, Trb3 Peptide, tribbles pseudokinase 3 Peptide, trib3 Peptide, TRIB3 Peptide, Trib3 Peptide
    Background
    The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1.

    Alias Symbols: C20orf97, NIPK, SINK, SKIP3, TRB3

    Protein Interaction Partner: ATF4,DDIT3,AKT1,AKT2,ATF4,C7orf64,COPS6,DDIT3,EEF1G,GDF9,GIT1,KAT5,RELA,SETDB1,AKT1,ATF4,ATF5,C7orf64,COPS6,CSNK2B,EEF1G,FN1,GDF9,GIT1,GRN,HLA-B,HRSP12,KAT5,LTBP4,MCM3AP,PSMA3,RBM4,RELA,RPSA,SETDB1,SIAH1,TIAF1,UBC

    Protein Size: 358
    Molecular Weight
    39 kDa
    Gene ID
    57761
    NCBI Accession
    NM_021158, NP_066981
    UniProt
    Q96RU7
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