Tribbles Homolog 3 (Drosophila) (TRIB3) (N-Term) Peptide
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- Target See all TRIB3 products
- TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- YVLLEPEEGG RAYQALHCPT GTEYTCKVYP VQEALAVLEP YARLPPHKHV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRIB3 Antibody(ARP57518_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
- Synonyms
- zgc:76966 Peptide, TRIB3 Peptide, C20orf97 Peptide, NIPK Peptide, SINK Peptide, SKIP3 Peptide, TRB3 Peptide, Ifld2 Peptide, Nipk Peptide, TRB-3 Peptide, Trb3 Peptide, tribbles pseudokinase 3 Peptide, trib3 Peptide, TRIB3 Peptide, Trib3 Peptide
- Background
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The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1.
Alias Symbols: C20orf97, NIPK, SINK, SKIP3, TRB3
Protein Interaction Partner: ATF4,DDIT3,AKT1,AKT2,ATF4,C7orf64,COPS6,DDIT3,EEF1G,GDF9,GIT1,KAT5,RELA,SETDB1,AKT1,ATF4,ATF5,C7orf64,COPS6,CSNK2B,EEF1G,FN1,GDF9,GIT1,GRN,HLA-B,HRSP12,KAT5,LTBP4,MCM3AP,PSMA3,RBM4,RELA,RPSA,SETDB1,SIAH1,TIAF1,UBC
Protein Size: 358 - Molecular Weight
- 39 kDa
- Gene ID
- 57761
- NCBI Accession
- NM_021158, NP_066981
- UniProt
- Q96RU7
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