Tripartite Motif Containing 24 (TRIM24) (Middle Region) Peptide
TRIM24
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TRIM24 products
- TRIM24 (Tripartite Motif Containing 24 (TRIM24))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRIM24 antibody (Catalog #: ARP34449_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TRIM24 (Tripartite Motif Containing 24 (TRIM24))
- Synonyms
- TRIM24 Peptide, PTC6 Peptide, RNF82 Peptide, TF1A Peptide, TIF1 Peptide, TIF1A Peptide, TIF1ALPHA Peptide, hTIF1 Peptide, ptc6 Peptide, rnf82 Peptide, tf1a Peptide, tif1 Peptide, tif1a Peptide, tif1alpha Peptide, A130082H20Rik Peptide, AI447469 Peptide, D430004I05Rik Peptide, TIF1-alpha Peptide, TIF1alpha Peptide, Tif1a Peptide, tripartite motif containing 24 Peptide, transcription intermediary factor 1-alpha Peptide, tripartite motif containing 24 S homeolog Peptide, tripartite motif-containing 24 Peptide, TRIM24 Peptide, trim24 Peptide, LOC100548578 Peptide, trim24.S Peptide, Trim24 Peptide
- Background
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The exact function of TRIM24 remains unknown. The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: PTC6, RNF82, TF1A, TIF1, TIF1A, TIF1ALPHA, hTIF1
Protein Interaction Partner: ESR1,AR,CBX1,CBX3,CBX5,ESR1,ESR2,GTF2E1,HNF4A,HSPA1A,NR2F2,NR3C1,NR3C2,PGR,PML,RARA,RXRA,SUMO1,TAF11,TAF1B,TAF1C,TAF7,THRA,TRIM24,TRIM28,TRIM33,VDR,ZNF10,AR,ESR1,GTF2E1,NR3C1,NR3C2,PML,RARA,RXRA,TAF11,TAF7,THRA,TRIM24,TRIM28,TRIM33,ZNF10
Protein Size: 1050 - Molecular Weight
- 117 kDa
- Gene ID
- 8805
- NCBI Accession
- NM_015905, NP_056989
- UniProt
- O15164
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