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Tripartite Motif Containing 25 (TRIM25) (Middle Region) Peptide

TRIM25 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN985502
  • Target See all TRIM25 products
    TRIM25 (Tripartite Motif Containing 25 (TRIM25))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    LLDASETTST RKIKEEEKRV NSKFDTIYQI LLKKKSEIQT LKEEIEQSLT
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-TRIM25 Antibody(ARP58105_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TRIM25 (Tripartite Motif Containing 25 (TRIM25))
    Synonyms
    zgc:55773 Peptide, MGC130751 Peptide, EFP Peptide, RNF147 Peptide, Z147 Peptide, ZNF147 Peptide, AA960166 Peptide, AL022677 Peptide, Zfp147 Peptide, Efp Peptide, Znf147 Peptide, E3 ubiquitin/ISG15 ligase TRIM25 Peptide, tripartite motif containing 25 Peptide, E3 ubiquitin/ISG15 ligase TRIM25-like L homeolog Peptide, microRNA 3614 Peptide, tripartite motif-containing 25 Peptide, LOC100146440 Peptide, trim25 Peptide, LOC100490741.L Peptide, TRIM25 Peptide, MIR3614 Peptide, Trim25 Peptide
    Background
    The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

    Alias Symbols: EFP, RNF147, Z147, ZNF147

    Protein Interaction Partner: SFN,TFG,TRIM25,UBE2L6,DDX58,ERCC2,ESR1,GATA1,ISG15,MEIS2,PITX2,RARRES3,SFN,STK38,TRIM25,UBC,UBE2D1,UBE2D2,UBE2D3,UBE2D4,UBE2J2,UBE2L6,UBE2N,ZNF24

    Protein Size: 630
    Molecular Weight
    71 kDa
    Gene ID
    7706
    NCBI Accession
    NM_005082, NP_005073
    UniProt
    Q14258
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