Thyroid Hormone Receptor Interactor 13 (TRIP13) (N-Term) Peptide
Quick Overview for Thyroid Hormone Receptor Interactor 13 (TRIP13) (N-Term) Peptide (ABIN985601)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- MDEAVGDLKQ ALPCVAESPT VHVEVHQRGS STAKKEDINL SVRKLLNRHN
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRIP13 Antibody(ARP38433_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))
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Background
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The thyroid hormone (T3) receptors (TRs) are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. TRIP13 specifically interacts with the ligand binding domain of the TRs. It is a member of Trips (TR-interacting proteins) family. Nearly all of the Trips also show similar ligand-dependent interaction with the retinoid X receptor (RXR), but none interact with the glucocorticoid receptor under any conditions. Trips predict specific functional roles: one is an apparent human homolog of a yeast transcriptional coactivator, one is a new member of a class of nonhistone chromosomal proteins, and one contains a conserved domain associated with ubiquitination of specific target proteins.
Alias Symbols: 16E1BP
Protein Interaction Partner: CD99,E1,ADAM15,ARL11,ASB13,C11orf54,C2orf51,CARD14,CD99,COMT,CPSF3L,CRMP1,CYB5R2,DDAH2,DTX2,GALT,GLYCTK,GPRIN2,GPSM1,HDHD3,KIAA1609,KRTAP3-2,LASP1,LNX1,LOXL4,MAD2L1BP,NIF3L1,NME4,PARK2,PBLD,PLAC8,PLK3,PLSCR3,PLSCR4,PPP2CA,RBPMS,SEC24A,SELENBP1,SEMA4G,SIGL
Protein Size: 432 -
Molecular Weight
- 48 kDa
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Gene ID
- 9319
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NCBI Accession
- NM_004237, NP_004228
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UniProt
- Q15645
Target
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