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Tetratricopeptide Repeat Domain 5 (TTC5) Peptide

TTC5 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN985714
  • Target See all TTC5 products
    TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-TTC5 antibody (Catalog #: ARP49004_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))
    Synonyms
    TTC5 Peptide, ttc5 Peptide, wu:fi33h05 Peptide, wu:fy81e07 Peptide, zgc:112059 Peptide, Strap Peptide, 5930437N14 Peptide, AW743060 Peptide, tetratricopeptide repeat domain 5 L homeolog Peptide, tetratricopeptide repeat domain 5 Peptide, ttc5.L Peptide, TTC5 Peptide, ttc5 Peptide, Ttc5 Peptide
    Background
    TTC5 is an adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. It is required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. It prevents p53/TP53 degradation by MDM2.

    Alias Symbols: Strap

    Protein Size: 440
    Molecular Weight
    49 kDa
    Gene ID
    91875
    NCBI Accession
    NM_138376, NP_612385
    UniProt
    Q8N0Z6
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