Thioredoxin Reductase 3 (TXNRD3) (N-Term) Peptide
TXNRD3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985782
$160.46
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100 μg
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Quick Overview for Thioredoxin Reductase 3 (TXNRD3) (N-Term) Peptide (ABIN985782)
Target
TXNRD3
(Thioredoxin Reductase 3 (TXNRD3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- LSPPGRRARL SSPGPSRSSE AREELRRHLV GLIERSRVVI FSKSYCPHST
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TXNRD3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TXNRD3 (Thioredoxin Reductase 3 (TXNRD3))
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Background
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This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. It contains a selenocysteine (Sec) residue (which is essential for catalytic activity), encoded by a UGA codon, at the penultimate C-terminal position. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: TGR, TR2, TRXR3
Protein Size: 643 -
Molecular Weight
- 70 kDa
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Gene ID
- 114112
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NCBI Accession
- NM_052883, NP_443115
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UniProt
- Q86VQ6
Target
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