U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) Peptide
U2AF59
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985792
$160.46
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100 μg
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Quick Overview for U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) Peptide (ABIN985792)
Target
U2AF2 (U2AF59)
(U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-U2AF2 antibody (Catalog #: ARP40284_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
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Background
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U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2AF2 is the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly.U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.
Alias Symbols: U2AF65
Protein Interaction Partner: BAT1,SF1,SF3B1,U2AF1,ATXN1,BEND7,C1orf190,CHIC2,CPSF7,DDX6,DPPA2,DVL2,EPB41,KIAA0907,MAP1B,PRPF40A,PUF60,SF1,SIP1,SMAD5,SRPK1,SRPK2,SRSF1,SRSF11,SRSF2IP,TCERG1,THAP1,U2AF1,WT1,ZRSR2,BEND7,C1orf190,CHIC2,DPPA2,DVL2,KIAA0907,PUF60,RNPS1,SF1,SF3A2,SRPK2,SRSF1,SRSF11,SRSF2IP,TCERG1,THAP1,U2AF1,WT1
Protein Size: 471 -
Molecular Weight
- 52 kDa
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Gene ID
- 11338
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NCBI Accession
- NM_001012478, NP_001012496
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UniProt
- Q96HC5
Target
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