U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) (C-Term) Peptide
U2AF59
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985793
$160.46
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100 μg
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Quick Overview for U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59) (C-Term) Peptide (ABIN985793)
Target
U2AF2 (U2AF59)
(U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- TEVLCLMNMV LPEELLDDEE YEEIVEDVRD ECSKYGLVKS IEIPRPVDGV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-U2AF2 Antibody,. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
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Background
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U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2AF2 is the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly.
Alias Symbols: U2AF65
Protein Interaction Partner: DDX39B,SF1,SF3B1,U2AF1,ATXN1,BEND7,C1orf190,CHIC2,CPSF7,DDX6,DPPA2,DVL2,EPB41,KIAA0907,MAP1B,PRPF40A,PUF60,SCAF11,SF1,SIP1,SMAD5,SRPK1,SRPK2,SRSF1,SRSF11,TCERG1,THAP1,U2AF1,WT1,ZRSR2,APBB1,BEND7,C1orf190,CHIC2,DPPA2,DVL2,GIGYF2,KIAA0907,PIN1,PRPF40A,PUF60
Protein Size: 471 -
Molecular Weight
- 53 kDa
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Gene ID
- 11338
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NCBI Accession
- NM_001012478, NP_001012496
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UniProt
- Q80XR5
Target
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