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Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) Peptide

UBE2L6 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN985831
  • Target See all UBE2L6 products
    UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-UBE2L6 antibody (Catalog #: ARP43033_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
    Synonyms
    UBE2L6 Peptide, RIG-B Peptide, UBCH8 Peptide, 2810489I21Rik Peptide, Ubce8 Peptide, Ubcm8 Peptide, UbcM8 Peptide, ubiquitin conjugating enzyme E2 L6 Peptide, ubiquitin-conjugating enzyme E2L 6 Peptide, UBE2L6 Peptide, Ube2l6 Peptide
    Background
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

    Alias Symbols: MGC40331, RIG-B, UBCH8

    Protein Interaction Partner: UBE3A,ARIH1,PARK2,RNF144B,RNF19A,RNF216,RNF40,SIAH2,SPEN,TRIM25,UBE3A,PARK2,RNF19A,RNF216,RNF40,SIAH2,TRIM25

    Protein Size: 153
    Molecular Weight
    18 kDa
    Gene ID
    9246
    NCBI Accession
    NM_004223, NP_004214
    UniProt
    Q8N5D8
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