Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) (N-Term) Peptide
UBE2V1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985843
Quick Overview for Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) (N-Term) Peptide (ABIN985843)
Target
UBE2V1
(Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- GEVQASYLKS QSKLSDEGRL EPRKFHCKGV KVPRNFRLLE ELEEGQKGVG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-UBE2V1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))
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Background
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Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Alias Symbols: CIR1, CROC-1, CROC1, UBE2V, UEV-1, UEV1, UEV1A
Protein Interaction Partner: KITLG,SUMO4,UBE2N,ARIH2,BIRC8,DTX3,DZIP3,MID1,MKRN3,RNF10,RNF111,RNF14,RNF144A,RNF185,RNF2,RNF5,STUB1,Stub1,TRAF2,TRAF6,TRIM32,TRIM39,TRIM5,TRIM8,UBE2N,UBOX5,XIAP,ZNRF1
Protein Size: 170 -
Molecular Weight
- 19 kDa
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Gene ID
- 7335
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NCBI Accession
- NM_021988, NP_068823
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UniProt
- Q13404
Target
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