WD Repeat Domain 5 (WDR5) (C-Term) Peptide
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- Target See all WDR5 products
- WDR5 (WD Repeat Domain 5 (WDR5))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Sequence
- LAGHTKAVSS VKFSPNGEWL ASSSADKLIK IWGAYDGKFE KTISGHKLGI
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-WDR5 Antibody(ARP41306_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- WDR5 (WD Repeat Domain 5 (WDR5))
- Synonyms
- BIG-3 Peptide, SWD3 Peptide, 2410008O07Rik Peptide, AA408785 Peptide, AA960360 Peptide, Big Peptide, Big-3 Peptide, zgc:56591 Peptide, zgc:76895 Peptide, wu:fk47f04 Peptide, wdr5-a Peptide, MGC80538 Peptide, wdr5-b Peptide, MGC81485 Peptide, big-3 Peptide, swd3 Peptide, xwdr5 Peptide, WDR5B Peptide, WD repeat domain 5 Peptide, WD repeat domain 5 L homeolog Peptide, WD repeat domain 5 S homeolog Peptide, WDR5 Peptide, Wdr5 Peptide, wdr5 Peptide, wdr5.L Peptide, wdr5.S Peptide
- Background
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This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.
Alias Symbols: BIG-3, SWD3
Protein Interaction Partner: MLL,ATN1,MBIP,MLL,ASH2L,CHD8,CIAO1,CUL4A,CUL4B,CXXC1,DTL,GRWD1,HCFC1,HCFC2,HIST1H3A,IKBKG,KDM6A,KIAA1267,MBIP,MEN1,MLL,MLLT1,MYB,NCOA6,NLE1,PAFAH1B1,PASK,PHF8,RBBP5,RFWD2,SETD1A,SETD1B,SNRNP40,WDR12,WDR26,WDR53,WDR59,WDR5B,WDR61,ZNF335,tat
Protein Size: 334 - Molecular Weight
- 36 kDa
- Gene ID
- 11091
- NCBI Accession
- NM_017588, NP_060058
- UniProt
- Q5M786
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