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WD Repeat Domain 5 (WDR5) (C-Term) Peptide

WDR5 Reactivity: Human Host: Synthetic BP, WB, IHC, IP
Catalog No. ABIN986170
  • Target See all WDR5 products
    WDR5 (WD Repeat Domain 5 (WDR5))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Sequence
    LAGHTKAVSS VKFSPNGEWL ASSSADKLIK IWGAYDGKFE KTISGHKLGI
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-WDR5 Antibody(ARP41306_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    WDR5 (WD Repeat Domain 5 (WDR5))
    Synonyms
    BIG-3 Peptide, SWD3 Peptide, 2410008O07Rik Peptide, AA408785 Peptide, AA960360 Peptide, Big Peptide, Big-3 Peptide, zgc:56591 Peptide, zgc:76895 Peptide, wu:fk47f04 Peptide, wdr5-a Peptide, MGC80538 Peptide, wdr5-b Peptide, MGC81485 Peptide, big-3 Peptide, swd3 Peptide, xwdr5 Peptide, WDR5B Peptide, WD repeat domain 5 Peptide, WD repeat domain 5 L homeolog Peptide, WD repeat domain 5 S homeolog Peptide, WDR5 Peptide, Wdr5 Peptide, wdr5 Peptide, wdr5.L Peptide, wdr5.S Peptide
    Background
    This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.

    Alias Symbols: BIG-3, SWD3

    Protein Interaction Partner: MLL,ATN1,MBIP,MLL,ASH2L,CHD8,CIAO1,CUL4A,CUL4B,CXXC1,DTL,GRWD1,HCFC1,HCFC2,HIST1H3A,IKBKG,KDM6A,KIAA1267,MBIP,MEN1,MLL,MLLT1,MYB,NCOA6,NLE1,PAFAH1B1,PASK,PHF8,RBBP5,RFWD2,SETD1A,SETD1B,SNRNP40,WDR12,WDR26,WDR53,WDR59,WDR5B,WDR61,ZNF335,tat

    Protein Size: 334
    Molecular Weight
    36 kDa
    Gene ID
    11091
    NCBI Accession
    NM_017588, NP_060058
    UniProt
    Q5M786
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