WD Repeat Domain 5 (WDR5) (C-Term) Peptide
WDR5
Reactivity: Human
Host: Synthetic
BP, WB, IHC, IP
Catalog No. ABIN986170
$160.46
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100 μg
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Quick Overview for WD Repeat Domain 5 (WDR5) (C-Term) Peptide (ABIN986170)
Target
WDR5
(WD Repeat Domain 5 (WDR5))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
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Protein Region
- C-Term
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Sequence
- LAGHTKAVSS VKFSPNGEWL ASSSADKLIK IWGAYDGKFE KTISGHKLGI
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-WDR5 Antibody(ARP41306_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- WDR5 (WD Repeat Domain 5 (WDR5))
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Background
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This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.
Alias Symbols: BIG-3, SWD3
Protein Interaction Partner: MLL,ATN1,MBIP,MLL,ASH2L,CHD8,CIAO1,CUL4A,CUL4B,CXXC1,DTL,GRWD1,HCFC1,HCFC2,HIST1H3A,IKBKG,KDM6A,KIAA1267,MBIP,MEN1,MLL,MLLT1,MYB,NCOA6,NLE1,PAFAH1B1,PASK,PHF8,RBBP5,RFWD2,SETD1A,SETD1B,SNRNP40,WDR12,WDR26,WDR53,WDR59,WDR5B,WDR61,ZNF335,tat
Protein Size: 334 -
Molecular Weight
- 36 kDa
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Gene ID
- 11091
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NCBI Accession
- NM_017588, NP_060058
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UniProt
- Q5M786
Target
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