WD Repeat Domain 5 (WDR5) (C-Term) Peptide
WDR5
Reactivity: Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN986171
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for WD Repeat Domain 5 (WDR5) (C-Term) Peptide (ABIN986171)
Target
WDR5
(WD Repeat Domain 5 (WDR5))
Origin
Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- NFSVTGGKWI VSGSEDNLVY IWNLQTKEIV QKLQGHTDVV ISTACHPTEN
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Wdr5 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- WDR5 (WD Repeat Domain 5 (WDR5))
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Background
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Wdr5 contributes to histone modification. It may position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. It may regulate osteoblasts differentiation.
Alias Symbols: 2410008O07Rik, AA408785, AA960360, Big, Big-3
Protein Interaction Partner: Esrrb,Kdm2b,Nr0b1,Pou5f1,Rnf2,Sall4,Tcfcp2l1
Protein Size: 334 -
Molecular Weight
- 36 kDa
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Gene ID
- 140858
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NCBI Accession
- NM_080848, NP_543124
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UniProt
- P61965
Target
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