WD Repeat Domain 5 (WDR5) (C-Term) Peptide
WDR5
Reactivity: Mouse
Host: Synthetic
BP, WB
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- Target See all WDR5 products
- WDR5 (WD Repeat Domain 5 (WDR5))
- Protein Region
- C-Term
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NFSVTGGKWI VSGSEDNLVY IWNLQTKEIV QKLQGHTDVV ISTACHPTEN
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Wdr5 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- WDR5 (WD Repeat Domain 5 (WDR5))
- Synonyms
- BIG-3 Peptide, SWD3 Peptide, 2410008O07Rik Peptide, AA408785 Peptide, AA960360 Peptide, Big Peptide, Big-3 Peptide, zgc:56591 Peptide, zgc:76895 Peptide, wu:fk47f04 Peptide, wdr5-a Peptide, MGC80538 Peptide, wdr5-b Peptide, MGC81485 Peptide, big-3 Peptide, swd3 Peptide, xwdr5 Peptide, WDR5B Peptide, WD repeat domain 5 Peptide, WD repeat domain 5 L homeolog Peptide, WD repeat domain 5 S homeolog Peptide, WDR5 Peptide, Wdr5 Peptide, wdr5 Peptide, wdr5.L Peptide, wdr5.S Peptide
- Background
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Wdr5 contributes to histone modification. It may position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. It may regulate osteoblasts differentiation.
Alias Symbols: 2410008O07Rik, AA408785, AA960360, Big, Big-3
Protein Interaction Partner: Esrrb,Kdm2b,Nr0b1,Pou5f1,Rnf2,Sall4,Tcfcp2l1
Protein Size: 334 - Molecular Weight
- 36 kDa
- Gene ID
- 140858
- NCBI Accession
- NM_080848, NP_543124
- UniProt
- P61965
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