(2 references)-
- Target
- Hgp100
- Protein Region
- AA 25-33
- Sequence
- One-letter code: KVPRNQDWL, Three-letter code: {Lys}{Val}{Pro}{Arg}{Asn}{Gln}{Asp}{Trp}{Leu
- Purity
- > 95 %
-
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Storage
- -20 °C
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: "Dendritic cell-directed lentivector vaccine induces antigen-specific immune responses against murine melanoma." in: Cancer gene therapy, Vol. 18, Issue 5, pp. 370-80, (2011) (PubMed).
: "Lentivector prime and vaccinia virus vector boost generate high-quality CD8 memory T cells and prevent autochthonous mouse melanoma." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 4, pp. 1788-96, (2011) (PubMed).
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: "Dendritic cell-directed lentivector vaccine induces antigen-specific immune responses against murine melanoma." in: Cancer gene therapy, Vol. 18, Issue 5, pp. 370-80, (2011) (PubMed).
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- Target
- Hgp100
- Background
- This is amino acids 25 to 33 fragment of human melanoma antigen gp100. This H-2Db restricted epitope is recognized by T cells. The gp100-specific, H-2Db-restricted, CD8+ T cells are capable of recognizing B16 melanoma but not normal melanocytes. This peptide was used as an immunogen in multiple cancer immunotherapy studies.
- Molecular Weight
- 1155.3
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