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PIEZO2 Products

(Family with Sequence Similarity 38, Member B (FAM38B))


Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains. 'Piezo' comes from the Greek 'piesi,' meaning 'pressure.' The PIEZO2 protein has a role in rapidly adapting mechanically activated (MA) currents in somatosensory neurons (Coste et al., 2010 [PubMed 20813920]).[supplied by OMIM, Nov 2010]. stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured PIEZO2 Categories

PIEZO2 Antibodies

High quality antibodies with extensive validation data.

Recommended PIEZO2 Antibodies

Cat. No.
Reactivity Human, Mouse, Rat
Application IHC, WB
  • (3)
Cat. No. ABIN7043133
Quantity 0.2 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
  • (1)
Cat. No. ABIN7244915
Quantity 200 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Guinea Pig, Human, Monkey, Mouse, Rabbit, Rat
Application WB
  • (1)
Cat. No. ABIN6738595
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PIEZO2 products

Mazzuoli-Weber, Kugler, Bühler, Kreutz, Demir, Ceyhan, Zeller, Schemann: "Piezo proteins: incidence and abundance in the enteric nervous system. Is there a link with mechanosensitivity?" in: Cell and tissue research, Vol. 375, Issue 3, pp. 605-618, (2019) (PubMed).

Alcaino, Knutson, Gottlieb, Farrugia, Beyder: "Mechanosensitive ion channel Piezo2 is inhibited by D-GsMTx4." in: Channels (Austin, Tex.), Vol. 11, Issue 3, pp. 245-253, (2018) (PubMed).

Narayanan, Hütte, Kudryasheva, Taberner, Lechner, Rehfeldt, Gomez-Varela, Schmidt: "Myotubularin related protein-2 and its phospholipid substrate PIP2 control Piezo2-mediated mechanotransduction in peripheral sensory neurons." in: eLife, Vol. 7, (2018) (PubMed).

Etem, Ceylan, Özaydın, Ceylan, Özercan, Kuloğlu: "The increased expression of Piezo1 and Piezo2 ion channels in human and mouse bladder carcinoma." in: Advances in clinical and experimental medicine : official organ Wroclaw Medical University, Vol. 27, Issue 8, pp. 1025-1031, (2018) (PubMed).

Nencini, Ivanusic: "Mechanically sensitive Aδ nociceptors that innervate bone marrow respond to changes in intra-osseous pressure." in: The Journal of physiology, (2017) (PubMed).

Florez-Paz, Bali, Kuner, Gomis: "A critical role for Piezo2 channels in the mechanotransduction of mouse proprioceptive neurons." in: Scientific reports, Vol. 6, pp. 25923, (2016) (PubMed).

Narayanan, Sondermann, Rouwette, Karaca, Urlaub, Mitkovski, Gomez-Varela, Schmidt: "Native Piezo2 Interactomics Identifies Pericentrin as a Novel Regulator of Piezo2 in Somatosensory Neurons." in: Journal of proteome research, Vol. 15, Issue 8, pp. 2676-87, (2016) (PubMed).

Poole, Herget, Lapatsina, Ngo, Lewin: "Tuning Piezo ion channels to detect molecular-scale movements relevant for fine touch." in: Nature communications, Vol. 5, pp. 3520, (2014) (PubMed).

Lee, Leddy, Chen, Lee, Zelenski, McNulty, Wu, Beicker, Coles, Zauscher, Grandl, Sachs, Guilak, Liedtke: "Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 47, pp. E5114-22, (2014) (PubMed).

Synonyms and alternative names related to PIEZO2

piezo type mechanosensitive ion channel component 2 (PIEZO2), piezo-type mechanosensitive ion channel component 2 (Piezo2), 5930434P17, 9030411M15Rik, 9430028L06Rik, C18orf30, C18orf58, FAM38B, Fam38b, FAM38B2, Fam38b2, HsT748, HsT771, RGD1306866

Protein level used designations for PIEZO2

  • family with sequence similarity 38, member B
  • family with sequence similarity 38, member B2
  • protein PIEZO2
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