PIAS1 Products
(Protein Inhibitor of Activated STAT, 1 (PIAS1))
Categories
This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. [provided by RefSeq, Jul 2008].
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Featured PIAS1 Categories
PIAS1 Antibodies
High quality antibodies with extensive validation data.
PIAS1 ELISA Kits
Reliable ELISA kits for a wide range of species.
PIAS1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PIAS1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), ICC
Validations
- (1)
- (6)
Cat. No.
ABIN3044474
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), ICC
Validations
- (10)
Cat. No.
ABIN3032369
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
Cat. No.
ABIN6264195
Quantity
100 μL
Datasheet
Datasheet
Recommended PIAS1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969707
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1381420
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative
Validations
Cat. No.
ABIN511795
Quantity
96 tests
Datasheet
Datasheet
Recommended PIAS1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1314985
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314988
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314986
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our PIAS1 products
: "The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion." in: JCI insight, Vol. 2, Issue 23, (2019) (PubMed).: "The effect of the TLR9 ligand CpG-oligodeoxynucleotide on the protective immune response to radiation-induced lung fibrosis in mice." in: Molecular immunology, Vol. 80, pp. 33-40, (2017) (PubMed).
: "CREB SUMOylation by the E3 ligase PIAS1 enhances spatial memory." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 29, pp. 9574-89, (2014) (PubMed).
: "Identification of novel interacting partners of Sirtuin6." in: PLoS ONE, Vol. 7, Issue 12, pp. e51555, (2012) (PubMed).
: "Substantially reduced expression of PIAS1 is associated with colon cancer development." in: Journal of cancer research and clinical oncology, Vol. 135, Issue 9, pp. 1287-91, (2009) (PubMed).
: "PIAS1 and PIASxalpha function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription." in: The Journal of biological chemistry, Vol. 277, Issue 44, pp. 41311-7, (2002) (PubMed).
: "Sumoylation of Mdm2 by protein inhibitor of activated STAT (PIAS) and RanBP2 enzymes." in: The Journal of biological chemistry, Vol. 277, Issue 51, pp. 50131-6, (2002) (PubMed).
: "Protein inhibitors of activated STAT resemble scaffold attachment factors and function as interacting nuclear receptor coregulators." in: The Journal of biological chemistry, Vol. 277, Issue 19, pp. 16993-7001, (2002) (PubMed).
Synonyms and alternative names related to PIAS1
protein inhibitor of activated STAT 1 (PIAS1), protein inhibitor of activated STAT 1 (Pias1), protein inhibitor of activated STAT, 1 (Pias1), protein inhibitor of activated STAT, 1a (pias1a), protein inhibitor of activated STAT 1 L homeolog (pias1.L), 2900068C24Rik, Ddxbp1, DDXBP1, ddxbp1, GBP, gbp, GU/RH-II, pias, pias1-A, xPAIS1, xPIAS1, ZMIZ3, zmiz3Protein level used designations for PIAS1
- protein inhibitor of activated STAT, 1
- DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1
- DEAD/H box-binding protein 1
- E3 SUMO-protein ligase PIAS1
- protein inhibitor of activated STAT protein 1
- AR interacting protein
- RNA helicase II-binding protein
- gu-binding protein
- protein inhibitor of activated STAT-1
- zinc finger, MIZ-type containing 3
- SUMO E3 ligase
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