PIAS2 Products
(Protein Inhibitor of Activated STAT, 2 (PIAS2))
Categories
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2011].
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Featured PIAS2 Categories
PIAS2 Antibodies
High quality antibodies with extensive validation data.
PIAS2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PIAS2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, PLA, RNAi
Validations
- (5)
Cat. No.
ABIN563927
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (4)
Cat. No.
ABIN6264196
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN522502
Quantity
50 μg
Datasheet
Datasheet
Recommended PIAS2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6206674
Quantity
96 tests
Datasheet
Datasheet
Recommended PIAS2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124649
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314991
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1788102
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our PIAS2 products
: "BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 27, pp. 11294-9, (2009) (PubMed).: "Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 44, pp. 16272-7, (2006) (PubMed).
: "FLI-1 functionally interacts with PIASxalpha, a member of the PIAS E3 SUMO ligase family." in: The Journal of biological chemistry, Vol. 280, Issue 45, pp. 38035-46, (2005) (PubMed).
: "A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells." in: The Journal of biological chemistry, Vol. 279, Issue 15, pp. 15505-14, (2004) (PubMed).
: "PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4." in: The Journal of biological chemistry, Vol. 278, Issue 24, pp. 21327-30, (2003) (PubMed).
: "Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter." in: Oncogene, Vol. 22, Issue 3, pp. 351-60, (2003) (PubMed).
: "Inhibition of Stat1-mediated gene activation by PIAS1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 18, pp. 10626-31, (1998) (PubMed).
Synonyms and alternative names related to PIAS2
protein inhibitor of activated STAT 2 L homeolog (pias2.L), protein inhibitor of activated STAT 2 (PIAS2), protein inhibitor of activated STAT, 2 (pias2), protein inhibitor of activated STAT 2 (Pias2), protein inhibitor of activated STAT, 2 (Pias2), 6330408K17Rik, AI462206, ARIP3, AU018068, Dib, DIP, MGC83751, MIZ, Miz1, MIZ1, PIAS2, piasx, PIASX, PIASX-ALPHA, PIASX-BETA, PIASxalpha, PIASxb, PIASxbeta, SIZ2, wu:fi05f09, ZMIZ4Protein level used designations for PIAS2
- protein inhibitor of activated STAT, 2
- protein inhibitor of activated STAT X
- protein inhibitor of activated STAT2
- E3 SUMO-protein ligase PIAS2
- E3 SUMO-protein ligase PIAS2-like
- e3 SUMO-protein ligase PIAS2-like
- DAB2-interacting protein
- DIP
- Msx-interacting-zinc finger
- PIASxalpha6
- androgen receptor-interacting protein 3
- msx-interacting zinc finger protein
- protein inhibitor of activated STAT x
- zinc finger, MIZ-type containing 4
- ARIP3
- msx-interacting-zinc finger protein
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