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PIGK Products

(GPI-anchor transamidase (GPI8))
This gene encodes a member of the cysteine protease family C13 that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is a member of the multisubunit enzyme, GPI transamidase and is thought to be its enzymatic component. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. [provided by RefSeq, Jul 2008].

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Featured PIGK Categories

PIGK Antibodies

High quality antibodies with extensive validation data.

PIGK ELISA Kits

Reliable ELISA kits for a wide range of species.

PIGK Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PIGK Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN389064
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN2856230
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC (p)
Validations
  • (3)
  • (2)
Cat. No. ABIN545261
Quantity 400 μL
Datasheet Datasheet

Recommended PIGK ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1135439
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1135440
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1135438
Quantity 96 tests
Datasheet Datasheet

Recommended PIGK Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315019
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3081110
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3128629
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PIGK products

Nagpal, Dasgupta, Jadallah, Chae, Ratovitski, Toubaji, Netto, Eagle, Nissan, Sidransky, Trink: "Profiling the expression pattern of GPI transamidase complex subunits in human cancer." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 21, Issue 8, pp. 979-91, (2008) (PubMed).

Ohishi, Nagamune, Maeda, Kinoshita: "Two subunits of glycosylphosphatidylinositol transamidase, GPI8 and PIG-T, form a functionally important intermolecular disulfide bridge." in: The Journal of biological chemistry, Vol. 278, Issue 16, pp. 13959-67, (2003) (PubMed).

Vainauskas, Maeda, Kurniawan, Kinoshita, Menon: "Structural requirements for the recruitment of Gaa1 into a functional glycosylphosphatidylinositol transamidase complex." in: The Journal of biological chemistry, Vol. 277, Issue 34, pp. 30535-42, (2002) (PubMed).

Ohishi, Inoue, Kinoshita: "PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8." in: The EMBO journal, Vol. 20, Issue 15, pp. 4088-98, (2001) (PubMed).

Synonyms and alternative names related to PIGK

phosphatidylinositol glycan anchor biosynthesis class K S homeolog (pigk.S), phosphatidylinositol glycan anchor biosynthesis class K (PIGK), phosphatidylinositol glycan anchor biosynthesis, class K (Pigk), phosphatidylinositol glycan anchor biosynthesis, class K (pigk), 3000001O05Rik, GPI8, zgc:86702

Protein level used designations for PIGK

  • GPI-anchor transamidase
  • phosphatidylinositol glycan, class K
  • GPI transamidase subunit
  • GPI8 homolog
  • PIG-K
  • phosphatidylinositol-glycan biosynthesis class K protein
  • GPI transamidase
  • phosphatidylinositol glycan class K
  • gpi8
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