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PLXND1 Products

(Plexin D1 (PLXND1))
Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Mediates anti-angiogenic signaling in response to SEMA3E. Required for normal development of the heart and vasculature.

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Featured PLXND1 Categories

PLXND1 Antibodies

High quality antibodies with extensive validation data.

PLXND1 ELISA Kits

Reliable ELISA kits for a wide range of species.

PLXND1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PLXND1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, FACS, IF
Validations
  • (6)
Cat. No. ABIN185358
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7163717
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC
Validations
  • (3)
Cat. No. ABIN2855942
Quantity 100 μL
Datasheet Datasheet

Recommended PLXND1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958665
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4884194
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6384911
Quantity 96 tests
Datasheet Datasheet

Recommended PLXND1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094612
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3135042
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094611
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PLXND1 products

Jurcak, Rucki, Muth, Thompson, Sharma, Ding, Zhu, Eshleman, Anders, Jaffee, Fujiwara, Zheng: "Axon Guidance Molecules Promote Perineural Invasion and Metastasis of Orthotopic Pancreatic Tumors in Mice." in: Gastroenterology, (2019) (PubMed).

Burk, Mire, Bellon, Hocine, Guillot, Moraes, Yoshida, Simons, Chauvet, Mann: "Post-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits." in: Nature communications, Vol. 8, pp. 14508, (2017) (PubMed).

Movassagh, Saati, Nandagopal, Mohammed, Tatari, Shan, Duke-Cohan, Fowke, Lin, Gounni: "Chemorepellent Semaphorin 3E Negatively Regulates Neutrophil Migration In Vitro and In Vivo." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 198, Issue 3, pp. 1023-1033, (2017) (PubMed).

Liu, Uemura, Fukushima, Yoshida, Hirashima: "Semaphorin 3G Provides a Repulsive Guidance Cue to Lymphatic Endothelial Cells via Neuropilin-2/PlexinD1." in: Cell reports, Vol. 17, Issue 9, pp. 2299-2311, (2016) (PubMed).

Lu, Evans, Hirano, Liu: "Dual role for Islet-1 in promoting striatonigral and repressing striatopallidal genetic programs to specify striatonigral cell identity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 1, pp. E168-77, (2014) (PubMed).

Tata, Stoppel, Hong, Ben-Zvi, Xie, Gu: "An image-based RNAi screen identifies SH3BP1 as a key effector of Semaphorin 3E-PlexinD1 signaling." in: The Journal of cell biology, Vol. 205, Issue 4, pp. 573-90, (2014) (PubMed).

Parikh, Eisner, Venugopalan, Yang, Lam, Bhattacharya: "Proteomic analyses of corneal tissue subjected to alkali exposure." in: Investigative ophthalmology & visual science, Vol. 52, Issue 3, pp. 1819-31, (2011) (PubMed).

Casazza, Finisguerra, Capparuccia, Camperi, Swiercz, Rizzolio, Rolny, Christensen, Bertotti, Sarotto, Risio, Trusolino, Weitz, Schneider, Mazzone, Mazzone, Comoglio, Tamagnone: "Sema3E-Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice." in: The Journal of clinical investigation, Vol. 120, Issue 8, pp. 2684-98, (2010) (PubMed).

Gu, Yoshida, Livet, Reimert, Mann, Merte, Henderson, Jessell, Kolodkin, Ginty: "Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins." in: Science (New York, N.Y.), Vol. 307, Issue 5707, pp. 265-8, (2005) (PubMed).

Synonyms and alternative names related to PLXND1

plexin D1 (PLXND1), plexin D1 (Plxnd1), plexin D1 (plxnd1), plexin-D1 (LOC100409974), 6230425C21Rik, b2b553Clo, PLEXD1, plexd1, zgc:77379

Protein level used designations for PLXND1

  • plexin-D1
  • obd
  • out of bounds
  • plexin D1
  • plexin-D1-like
  • LOW QUALITY PROTEIN: plexin-D1
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