PNPLA6 Products
(Patatin-Like phospholipase Domain Containing 6 (PNPLA6))
Categories
This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
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Featured PNPLA6 Categories
PNPLA6 Antibodies
High quality antibodies with extensive validation data.
PNPLA6 ELISA Kits
Reliable ELISA kits for a wide range of species.
PNPLA6 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PNPLA6 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (4)
Cat. No.
ABIN3187873
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (4)
Cat. No.
ABIN524312
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7161406
Quantity
100 μg
Datasheet
Datasheet
Recommended PNPLA6 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969162
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958421
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1144900
Quantity
96 tests
Datasheet
Datasheet
Recommended PNPLA6 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315591
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3134983
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
Cat. No.
ABIN3134984
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PNPLA6 products
: "Loss-of-function mutations in PNPLA6 encoding neuropathy target esterase underlie pubertal failure and neurological deficits in Gordon Holmes syndrome." in: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 10, pp. E2067-75, (2014) (PubMed).: "Neuropathy target esterase gene mutations cause motor neuron disease." in: American journal of human genetics, Vol. 82, Issue 3, pp. 780-5, (2008) (PubMed).
: "Loss of neuropathy target esterase in mice links organophosphate exposure to hyperactivity." in: Nature genetics, Vol. 33, Issue 4, pp. 477-85, (2003) (PubMed).
Synonyms and alternative names related to PNPLA6
patatin like phospholipase domain containing 6 (PNPLA6), patatin-like phospholipase domain containing 6 (Pnpla6), patatin-like phospholipase domain containing 6 (pnpla6), patatin like phospholipase domain containing 6 (Pnpla6), AI661849, iPLA2delta, MSws, NTE, Nte, NTEMND, RGD1564611, SPG39, sws, wu:fy20f06Protein level used designations for PNPLA6
- neuropathy target esterase
- patatin-like phospholipase domain-containing protein 6
- Swiss cheese
- Swiss-cheese
- nte
- LOW QUALITY PROTEIN: neuropathy target esterase
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